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Voitto Lippu
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Liittynyt: 24 Tou 2005
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Paikkakunta: Espoo, Finland
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 Lähetetty: 30.9.2014 5:19 Viestin aihe: Sirirat sairaalan vasta-aine ebolaan |
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Sirirat sairaalan tutkimuslaitoksen on sanottu löytäneen vasta-aineen ebola-kuumeeseen.
http://www.nationmultimedia.com/national/Siriraj-comes-up-with-an-antibody-for-Ebola-30244418.html
| Lainaus: | Siriraj comes up with an |antibody for Ebola
The Nation September 30, 2014 1:00 am
A THAI medical school has successfully produced an antibody for the treatment of the deadly Ebola haemorrhagic fever.
Mahidol University's Faculty of Medicine Siriraj Hospital is preparing to announce its success at a press conference scheduled for Thursday.
This medical breakthrough marks the first time that Thailand has been able to produce such an antibody.
Present at the event will be the faculty's dean Udom Kachintorn and a team of doctors and researchers.
Though there has never been an Ebola infection in Thailand, the disease has been posing a haunting threat this year as it has claimed many lives in Africa. Many people from the Ebola-hit continent have travelled to Bangkok, which is an aviation hub.
The mortality rate for the disease is high.
According to MedLine Plus, a service of the US National Library of Medicine, as many as 90 per cent of Ebola patients finally succumb to the disease. Patients usually die from low blood pressure than from blood loss.
There is no known cure. Existing antiviral medication does not work well against the Ebola virus. Treatment for the massive drop in blood pressure includes medication and fluids given intravenously.
Bleeding problems may require transfusions of platelets or fresh blood.
The antibody that the Faculty of Medicine Siriraj Hospital has produced, therefore, can be of crucial importance for the treatment. |
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http://bamboogrovestories.blogspot.com/
Ei sillä ole väliä onko kissa musta vai valkoinen, kunhan se vaan pyydystää hiiriä.
Paluu Bambulehtoon näkyvissä. |
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Voitto Lippu
Administrator ผู้บริหาร
Liittynyt: 24 Tou 2005
Viestejä: 10949
Paikkakunta: Espoo, Finland
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| Lähetetty: 3.10.2014 5:32 Viestin aihe: |
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Tutkijat ovat valmiita aloittamaan tutkimukset eläimillä ja ihmisillä.
| Lainaus: | Mahidol Faculty at Siriraj patents antibody for ebola haemorrhagic fever
A THAI medical school has achieved a breakthrough in the treatment of the deadly Ebola Haemorrhagic Fever (EHF), with the potential for commercial distribution within one year from now and boosting the world's hope of combating the deadly disease that has already claimed thousands of lives in Africa this year.
At a press conference, Mahidol University's Faculty of Medicine Siriraj Hospital yesterday announced that this breakthrough was the therapeutic antibody for EHF.
"If we can produce it in a huge volume, we are willing to send it to patients in Africa," the faculty's dean, clinical Prof Dr Udom Kachintorn, said. At this point, the therapeutic-antibody production is still on a laboratory scale.
He said a new drug could be used in humans infected with diseases like EHF even when it had not yet completed the process of testing on animals and humans.
Prof Dr Wanpen Chaicumpa, who led the research team on this medical breakthrough, said her faculty would inform the World Health Organisation about this success in the hope that further cooperation would speed up development at the next step.
She said the antibody treatment was set to be tested on monkeys and humans in the next few months at a private laboratory, arranged via her institute's cooperation with the University of Florida in the United States.
Wanpen said the therapeutic antibody created by her team had many special characteristics. "For example, it is very small, is able to enter infected cells and is thus accessible to the intracellular virus proteins. It should then be able to help stop the virus production in the infected cells," she said, adding that her faculty had already patented the innovation.
Prof Ruengpung Sutthent, deputy dean of research at the same faculty, said one of the major challenges for further development of the antibody treatment was the limited laboratory capacity.
The research team now hopes the government will financially support further research on Ebola antibody development. It expects further research to require about Bt1 billion budget.
The team, for example, points out that it will need a better-equipped lab to conduct further research.
In regard to antibody treatment trials on animals, the Faculty of Medicine Siriraj Hospital plans to collaborate with Siam Bioscience Co. This biopharmaceutical company, partly owned by Mahidol University, has the capacity to produce bioproducts at manufacturing scale and to generate more antibodies under good manufacturing practice standards for further animal trials.
Meanwhile, the WHO said two experimental vaccines for EHF, being developed by GlaxoSmithKline and the Public Health Agency of Canada, look promising and have supplies ready to start human clinical trials.
Trials will be conducted on healthy people in the UK and the US, the WHO said, and would evaluate the safety of the vaccines and their ability to generate an immune-response in humans.
At present, there is no cure for Ebola, which is spread by contact with blood and bodily fluids of those infected. The disease is normally treated by keeping patients hydrated, replacing lost blood and using antibiotics to fight infections |
http://www.nationmultimedia.com/national/Thai-researchers-breakthrough-30244670.html
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http://bamboogrovestories.blogspot.com/
Ei sillä ole väliä onko kissa musta vai valkoinen, kunhan se vaan pyydystää hiiriä.
Paluu Bambulehtoon näkyvissä. |
|
| Takaisin alkuun |
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Voitto Lippu
Administrator ผู้บริหาร
Liittynyt: 24 Tou 2005
Viestejä: 10949
Paikkakunta: Espoo, Finland
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| Lähetetty: 4.10.2014 9:16 Viestin aihe: |
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WHO on luonnollisesti myös kiinnostunut asiasta ja on nyt pyytänyt näytteen vasta-aineesta.
| Lainaus: | WHO seeks to test Thai antibody
Puangchumpoo Prasert
Wasu Wipoosanapat
The Nation October 4, 2014 1:00 am
WORLD ORGANISATION WANTS TO TEST SIRIRAJ HOSPITAL BREAKTHROUGH ON ACTUAL VIRUS BEFORE CLINICAL TRIALS
The World Health Organisation has made a request to test an antibody developed by Siriraj Hospital for Ebola treatment, according to the head of the facility's medical faculty.
Clinical Prof Dr Udom Kachintorn, dean of Mahidol University's Faculty of Medicine, said he received an e-mail from WHO's head of Ebola research, Dr Martin Friede, asking for the antibody so the organisation could authenticate the achievement and use the treatment.
The medical school at Siriraj Hospital claimed this week that it had successfully developed the antibody for the treatment of the deadly Ebola Haemorrhagic Fever (EHF).
WHO praised the achievement and wanted to use the antibody to combat in the deadly virus, he said.
Ebola has killed more than 3,000 mostly Africans this year.
Udom said the antibody had successfully fought an artificial Ebola virus developed in a lab and WHO wanted to test it on the actual virus before staging clinical trials on animals and humans.
"If it works, this method could shorten the clinical-trial procedure and be developed for EHF treatment in humans," he said.
Udom said Thailand should have better medical research facilities in order to improve the country's medical research ability, and at the very least it should have a level-four biosafety laboratory.
Thailand currently had a level-three laboratory, which was not safe enough for research and trails.
Udom said many healthcare personnel and medical experts were infected with the Ebola virus while treating people or working in a lab.
He said Siriraj Hospital had invested Bt12 million in developing a safety system for medical research that gave researchers total protection.
Meanwhile, Prof Dr Wanpen Chaicumpa, who led the research team that developed the antibody, said she was in the process of selecting the five best antibodies among 100 clones and would then forward them to WHO - a process that would take a few weeks.
Wanpen said that despite the organisation's interest it was important its representatives arranged a formal discussion with Siriraj Hospital, which owned the patent, and the Ministry of Public Heath to ensure the hospital was engaged during the tests.
She said that since the tests would be done in a level-four biosafety laboratory, it would help lessen the time of the procedure, which usually required tests on animals and humans, but it still could take up to a year.
Dr Apichai Mongkol, the Public Health Ministry's Medical Science Department director-general, said his department had already asked for approval from the ministry to develop a level-four biosafety laboratory.
Apichai said the ministry had not yet considered the request, which would require a Bt57-million budget, due to the political strife earlier this year.
It was expected that the proposal would be considered when new Health Minister Rajata Rajatanavin had the time to look at it in detail. |
http://www.nationmultimedia.com/national/WHO-seeks-to-test-Thai-antibody-30244753.html
_________________
http://bamboogrovestories.blogspot.com/
Ei sillä ole väliä onko kissa musta vai valkoinen, kunhan se vaan pyydystää hiiriä.
Paluu Bambulehtoon näkyvissä. |
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| Takaisin alkuun |
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spiigeli
Administrator ผู้บริหาร
Liittynyt: 28 Tou 2005
Viestejä: 10505
Paikkakunta: Helsinki
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| Lähetetty: 4.10.2014 14:11 Viestin aihe: |
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Thaimaalaiset tuntuu aina ottavan vakavasti vierasperäiset taudit.
Tutkimus ja kehitystyö tuntuu olevan huippua.
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